Lidocaine intrauterine gel1.
1. Lidbree SmPC.
2. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7
3 Maria Joăo Carvalho et. al. Patient’s satisfaction considering office hysteroscopy using lidocaine termogel 4%: short-acting lidocaine technology (SHACT) multicentre study. ESGE 2023 32nd Annual Congress. Poster
2. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7
3 Maria Joăo Carvalho et. al. Patient’s satisfaction considering office hysteroscopy using lidocaine termogel 4%: short-acting lidocaine technology (SHACT) multicentre study. ESGE 2023 32nd Annual Congress. Poster
What is Lidbree like?
*The efficacy and safety of Lidbree as a topical anaesthetic for cervical and intrauterine procedures was demonstrated in a pain model: a multicentre, placebo-controlled study in 218 nulliparous women requesting
placement of an intrauterine contraceptive device (IUD).1.
IUD: intrauterine device.
1. Lidbree SmPC.; 2. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7.[1.] Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7
1. Lidbree SmPC.; 2. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7.[1.] Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7
Lidbree is administered exclusively by endocervical and intrauterine routes1.
*If a gel forms, chill until it becomes liquid again.1.
1. Lidbree SmPC.
1. Lidbree SmPC.
New topical local anaesthetic formulation for cervical and intrauterine gynaecological procedures1,2
1. Lidbree SmPC.; 2. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7.
IUD insertion is a routine gynaecological procedure1.
IUD: intrauterine device.
1. OMS. Family Planning: A Global Handbook for Providers (3ª edición, 2018); 2. Ireland LD, Allen RH. Obstet Gynecol Surv 2016;71:89-98; 3. Lopez LM, et al. Cochrane Database Syst Rev 2015;7:CD007373.
4. Asker C, et al. J Fam Plann Reprod Health Care. 2006 Apr;32(2):89-94.
1. OMS. Family Planning: A Global Handbook for Providers (3ª edición, 2018); 2. Ireland LD, Allen RH. Obstet Gynecol Surv 2016;71:89-98; 3. Lopez LM, et al. Cochrane Database Syst Rev 2015;7:CD007373.
4. Asker C, et al. J Fam Plann Reprod Health Care. 2006 Apr;32(2):89-94.
Gynecologists underestimate pain during IUD insertion1.?
SD: standard deviation; VAS: visual analogue scale; IUD: intrauterine device.
1. Maguire K, et al. Contraception. 2014 Jan;89(1):22-4.
1. Maguire K, et al. Contraception. 2014 Jan;89(1):22-4.
New topical formulation of lidocaine for cervical and intrauterine administration1,2
1. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7; 2. Lidbree SmPC.
Lidbree significantly reduces pain during IUD insertion1
IUD: intrauterine device; VAS: visual analogue scale.
1. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7; 2. Lidbree SmPC.
1. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7; 2. Lidbree SmPC.
A higher percentage of women in the lidocaine group felt no discomfort after administration of the study drug1
5 women in the lidocaine group and 16 in the placebo group reported very severe discomfort.1
1. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7.
30 minutes after IUD insertion, the mean VAS pain score remained lower in the lidocaine group compared to the placebo group1
IUD: intrauterine device; VAS: visual analogue scale.
1. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7
1. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7
Lidocaine formulation provides pain reduction without any serious adverse event1
1. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7
Sensation of pain in the female reproductive tract
* Abdominal pain is pain arising from distension, injury or inflammation of hollow organs1
1. Jobling P, et al. Front Pharmacol 2014;5:17
1. Jobling P, et al. Front Pharmacol 2014;5:17
Painful stimuli during intrauterine gynaecological procedures
IUD: intrauterine device.
1. Lidbree SmPC.
1. Lidbree SmPC.
Hysteroscopies
1. Ahmad G, et al. Cochrane Database Syst Rev. 2017: CD007710; 2. Ireland LD, Allen RH. Obstet Gynecol Surv 2016;71:89-98.
Cervical and endometrial biopsies
1. Ireland LD, Allen RH. Obstet Gynecol Surv 2016;71:89-98.
Lidbree acts as a local anaesthetic in cervical and intrauterine procedures within 5 minutes of administration1
1. Lidbree SmPC.; 2. Tornblom-Paulander S, et al. Fertil Steril. 2015 Feb;103(2):422-7
